Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16861345 | 0.74 | MEN1 (0.38) | PTGDR2MEN1KMT2ASLC6A3PDE4B | |
| SCHEMBL10698433 | 0.70 | DHFR (0.35) | PTPN1SLC6A3 | |
| SCHEMBL5701695 | 0.70 | PDE4B (0.39) | PDE4BCYSLTR2CYSLTR1 | |
| SCHEMBL7241509 | 0.70 | KMT2A (0.45) | PTPN1KMT2A | |
| SCHEMBL31233313 | 0.69 | PTPN1 (0.43) | PTPN1MEN1KMT2ASLC6A3PDE4B | |
| SCHEMBL7221504 | 0.69 | HPGD (0.44) | PTPN1MEN1KMT2APDE4B | |
| SCHEMBL11769897 | 0.69 | SLC6A3 (0.38) | PTPN1MEN1KMT2ASLC6A3PDE4B | |
| SCHEMBL16861299 | 0.69 | MEN1 (0.33) | PTGDR2MEN1KMT2ASLC6A3PDE4B | |
| SCHEMBL17537137 | 0.68 | PTPN1 (0.36) | PTPN1MEN1KMT2ASLC6A3PDE4B | |
| SCHEMBL11766287 | 0.68 | PTPN1 (0.37) | PTPN1MEN1KMT2ASLC6A3PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271287-A2 | Quinoline dioic acids and amides | MERCK FROSST CANADA INC. (CA) | 1988-06-15 | — | — | EP | disclosed |