Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696569 | 0.91 | MEN1 (0.36) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11007482 | 0.89 | MEN1 (0.48) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10699015 | 0.89 | TDP1 (0.42) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10696298 | 0.87 | ALDH1A1 (0.34) | MEN1KMT2ATDP1PPARDALDH1A1 | |
| SCHEMBL10696366 | 0.82 | RAB9A (0.35) | TDP1ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL10697769 | 0.79 | TDP1 (0.38) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11036501 | 0.77 | KMT2A (0.44) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11010421 | 0.77 | MERTK (0.48) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL30806808 | 0.77 | MERTK (0.48) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL11118813 | 0.76 | MEN1 (0.50) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |