Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884613 | 0.80 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4187236 | 0.78 | MAPT (0.51) | MAPTLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL1492578 | 0.78 | KDM4E (0.55) | MAPTLMNAPOLBRXFP1ALDH1A1 | |
| SCHEMBL14444533 | 0.78 | MAPT (0.52) | MAPTLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL6255747 | 0.77 | MAPT (0.50) | MAPTLMNAPOLBALDH1A1KDM4E | |
| SCHEMBL3928261 | 0.76 | MAPT (0.50) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL9058875 | 0.76 | KDM4E (0.54) | MAPTLMNAPOLBRXFP1ALDH1A1 | |
| SCHEMBL10695516 | 0.76 | CXCR1 (0.53) | MAPTPOLBRXFP1ALDH1A1KDM4E | |
| SCHEMBL31275741 | 0.75 | MAPT (0.60) | MAPTLMNAPOLBALDH1A1KDM4E | |
| SCHEMBL5802564 | 0.75 | MAPT (0.62) | MAPTLMNAALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | disclosed |
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |