Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138319 | 0.82 | MAPT (0.49) | CYP2C19POLBRXFP1MAPTPKM | |
| SCHEMBL4492921 | 0.80 | CYP1A2 (0.54) | CYP2C19POLBRXFP1GSTP1GSTM2 | |
| SCHEMBL12526399 | 0.78 | CYP2C19 (0.50) | CYP2C19POLBMAPTCYP1A2GAA | |
| SCHEMBL3249905 | 0.78 | ALDH1A1 (0.55) | POLBRXFP1MAPTKDM4EALDH1A1 | |
| SCHEMBL25249940 | 0.78 | CXCR2 (0.65) | CXCR1CXCR2CYP2C19POLBMAPT | |
| SCHEMBL16456689 | 0.78 | CXCR1 (0.51) | CXCR1CXCR2CYP2C19POLBRXFP1 | |
| SCHEMBL4500668 | 0.76 | CYP2C19 (0.48) | CYP2C19POLBRXFP1MAPTCYP1A2 | |
| SCHEMBL10697491 | 0.76 | MAPT (0.61) | POLBRXFP1MAPTKDM4EALDH1A1 | |
| SCHEMBL29170274 | 0.76 | RAB9A (0.56) | CYP2C19POLBMAPTCYP1A2GAA | |
| SCHEMBL20471548 | 0.75 | TDP1 (0.42) | CYP2C19POLBRXFP1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |