SCHEMBL10697508

SCHEMBL10697508

CC(Oc1ccccc1Cl)Oc1cccc(C(=O)O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.47
TP53 P04637 1/20 0.47
ALDH1A1 P00352 8/20 0.46
TSHR P16473 3/20 0.44
KDM4E B2RXH2 6/20 0.43
HSD17B10 Q99714 6/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
RXFP1 Q9HBX9 1/20 0.43
HPGD P15428 7/20 0.43
MAPT P10636 3/20 0.43
ESR1 P03372 2/20 0.42
ESR2 Q92731 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
PTGS2 P35354 2/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
GGT1 P19440 1/20 0.41
PTGS1 P23219 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9551794 0.85 ALDH1A1 (0.45) HTTALDH1A1TSHRKDM4EHSD17B10
SCHEMBL10697509 0.80 HTT (0.47) HTTTP53ALDH1A1TSHRKDM4E
SCHEMBL30625923 0.80 IRAK4 (0.54) HTTALDH1A1TSHRKDM4EHSD17B10
SCHEMBL9395756 0.79 KDM4E (0.43) HTTTP53ALDH1A1TSHRKDM4E
SCHEMBL10599621 0.79 ALDH1A1 (0.45) ALDH1A1TSHRKDM4EHSD17B10KMT2A
SCHEMBL9129853 0.79 KDM4E (0.50) HTTALDH1A1TSHRKDM4EHSD17B10
SCHEMBL10619157 0.78 KDM4E (0.59) HTTALDH1A1TSHRKDM4EHSD17B10
SCHEMBL10709666 0.78 ADRA2A (0.49) ALDH1A1TSHRMEN1KMT2AHPGD
SCHEMBL10697129 0.77 KDM4E (0.40) HTTALDH1A1TSHRKDM4EHSD17B10
SCHEMBL10698533 0.77 ALDH1A1 (0.46) ALDH1A1TSHRKDM4EHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed