Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 5/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699694 | 0.98 | TSHR (0.45) | TSHRHCAR2FAAHNAAADGKA | |
| SCHEMBL9863424 | 0.95 | ALDH1A1 (0.39) | TSHRHCAR2FAAHDGKAALDH1A1 | |
| SCHEMBL10697528 | 0.78 | TSHR (0.33) | TSHRHCAR2FAAHCES2 | |
| SCHEMBL10698706 | 0.78 | TSHR (0.33) | TSHRHCAR2FAAHCES2 | |
| SCHEMBL10699697 | 0.77 | TSHR (0.36) | TSHRHCAR2FAAHNAAACES2 | |
| SCHEMBL10697692 | 0.77 | TSHR (0.36) | TSHRHCAR2FAAHNAAACES2 | |
| SCHEMBL10701514 | 0.75 | HCAR2 (0.56) | TSHRHCAR2NAAADGKANPSR1 | |
| SCHEMBL10699808 | 0.74 | HCAR2 (0.57) | TSHRHCAR2NAAADGKANPSR1 | |
| SCHEMBL27887656 | 0.74 | TSHR (0.55) | TSHRHCAR2FAAHNAAAALDH1A1 | |
| SCHEMBL9863427 | 0.74 | ALDH1A1 (0.33) | HCAR2FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289933-A2 | Graft polymerization precurser and method manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0277608-A2 | Graft polymerization preformer and method of manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |