Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698706 | 0.99 | TSHR (0.33) | TSHRCES2HCAR2FAAHTHRA | |
| SCHEMBL10697688 | 0.90 | TSHR (0.36) | TSHRCES2HCAR2FAAHNAAA | |
| SCHEMBL10699694 | 0.79 | TSHR (0.45) | TSHRCES2HCAR2FAAHNAAA | |
| SCHEMBL10697523 | 0.77 | TSHR (0.42) | TSHRCES2HCAR2FAAHNAAA | |
| SCHEMBL10698748 | 0.76 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL10699697 | 0.76 | TSHR (0.36) | TSHRCES2HCAR2FAAHNAAA | |
| SCHEMBL1581663 | 0.75 | NAAA (0.40) | TSHRCES2HCAR2HSD17B10NAAA | |
| SCHEMBL10697528 | 0.74 | TSHR (0.33) | TSHRCES2HCAR2FAAH | |
| SCHEMBL8762563 | 0.73 | — | — | |
| SCHEMBL8593909 | 0.73 | NAAA (0.37) | TSHRCES2HCAR2GMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289933-A2 | Graft polymerization precurser and method manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0277608-A2 | Graft polymerization preformer and method of manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |