Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 14/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696447 | 0.82 | PIK3CG (0.46) | PIK3CGPI4KBPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9835802 | 0.79 | ABL1 (0.45) | — | |
| SCHEMBL10696710 | 0.77 | CHRM2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL10698643 | 0.72 | DHFR (0.42) | — | |
| SCHEMBL9833430 | 0.72 | DHFR (0.42) | — | |
| SCHEMBL10698179 | 0.69 | TYR (0.45) | PI4KB | |
| SCHEMBL4200805 | 0.66 | PIK3CG (0.58) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL924757 | 0.66 | PIK3CG (0.50) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9728494 | 0.65 | CHRM2 (0.45) | — | |
| SCHEMBL9729003 | 0.65 | CHRM2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |