Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698534 | 0.79 | HTR6 (0.39) | KCNH2SIGMAR1 | |
| SCHEMBL9728716 | 0.78 | CHRM2 (0.41) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL10697534 | 0.77 | PIK3CG (0.46) | — | |
| SCHEMBL9451955 | 0.76 | CHRM2 (0.46) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9728494 | 0.71 | CHRM2 (0.45) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9451932 | 0.69 | CHRM2 (0.48) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9728560 | 0.69 | — | — | |
| SCHEMBL9451944 | 0.68 | — | — | |
| SCHEMBL9452006 | 0.68 | CHRM2 (0.44) | CHRM2CHRM4CHRM5ADRA2AADRA2B | |
| SCHEMBL9833971 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |