Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27330369 | 0.95 | TSHR (0.54) | TSHRNAPRTTDP1CYP2A6ATM | |
| Pyrimidine SCHEMBL27818622 | 0.95 | TSHR (0.54) | TSHRNAPRTTDP1CYP2A6ATM | |
| Pyrimidine SCHEMBL1846 | 0.95 | — | — | |
| Pyrimidine SCHEMBL10646 | 0.95 | TSHR (0.50) | TSHRNAPRTTDP1CYP2A6ATM | |
| Pyrimidine SCHEMBL19437633 | 0.95 | TSHR (0.50) | TSHRNAPRTTDP1CYP2A6ATM | |
| SCHEMBL30672626 | 0.91 | TSHR (0.75) | TSHRNAPRTTDP1CYP2A6ATM | |
| Pyridine SCHEMBL902582 | 0.91 | TSHR (0.75) | TSHRNAPRTTDP1CYP2A6ATM | |
| Pyridine SCHEMBL4996631 | 0.91 | TSHR (0.75) | TSHRNAPRTTDP1CYP2A6ATM | |
| Benzene SCHEMBL12496012 | 0.91 | TSHR (0.75) | TSHRNAPRTTDP1CYP2A6ATM | |
| SCHEMBL31038354 | 0.91 | TSHR (0.75) | TSHRNAPRTTDP1CYP2A6ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110402941-A | A kind of pyrrole metsulfovax and trifluoro-benzene pyrimidine mixed insecticide preparation | JING YOUCHAO | 2019-11-05 | — | — | CN | claimed |
| CN-110067084-A | The preparation process and application of a kind of long yarns of superelevation branch PI electrospinning fibre | 江西先材纳米纤维科技有限公司 | 2019-07-30 | — | — | CN | claimed |
| CN-109197867-A | Diaphorina citri attracticide and its preparation method and application | 柳州东雅科技有限公司 | 2019-01-15 | — | — | CN | claimed |
| CN-108007883-A | A kind of application of three key of pyrimidine-benzene alternating conjugated polymer in mercury ion detecting | 新疆大学 | 2018-05-08 | — | — | CN | claimed |
| CN-102370967-A | Novel application of IL-1Ra (interleukin-1 receptor antagonist) and tumor treatment medicinal composition kit thereof | UNIV SHANGHAI JIAOTONG | 2012-03-14 | — | — | CN | claimed |
| EP-0255100-A2 | Use of trimetrexate and its salts for the preparation of pharmaceutical compositions for treating infections of the mycobacterium-avium-intracellulare complex | WARNER-LAMBERT COMPANY (US) | 1988-02-03 | — | — | EP | claimed |
| CN-109641940-B | Protoporphyrinogen oxidase variants and methods and compositions for conferring and/or enhancing herbicide tolerance using the same | 福阿母韩农株式会社 | 2022-11-18 | — | — | CN | disclosed |
| CN-113891714-A | Triple therapy to enhance cancer cell killing in low immunogenic cancers | 大连万春布林医药有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-110495463-A | The Synergistic insecticidal composition of the pyrimidine containing trifluoro-benzene and its application | TAIAN ACAD OF AGRICULTURAL SCIENCES | 2019-11-26 | — | — | CN | disclosed |
| CN-110200019-A | Kill the composition of planthopper | 重庆谷百奥生物研究院有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-110023303-A | Tetrazolinone compounds and their use as pest control agents | 住友化学株式会社 | 2019-07-16 | — | — | CN | disclosed |
| CN-109805013-A | A kind of composition pesticide for seed treatment | 广东中迅农科股份有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-109769842-A | A kind of insecticide composition containing trifluoro-benzene pyrimidine, rotenoid | 广西化工研究院有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-1897928-A | Novel alanyl-amino peptidase inhibitors for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases | IMTM GMBH (DE) | 2007-01-17 | — | — | CN | disclosed |
| CN-1889960-A | Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases | INST MEDIZINTECHNOLOGIE MAGDEB (DE) | 2007-01-03 | — | — | CN | disclosed |
| CN-1882332-A | Dual alanyl aminopeptidase and dipeptidyl peptidase IV inhibitors for functionally influencing different types of cells and for the treatment of immune, inflammatory, neurological and other diseases | IMTM GMBH (DE) | 2006-12-20 | — | — | CN | disclosed |
| CN-1774464-A | Dendrimer and electronic device element using the same | SHARP KK (JP) | 2006-05-17 | — | — | CN | disclosed |
| CN-1064138-C | Liquid crystal device | CANON KK (JP) | 2001-04-04 | — | — | CN | disclosed |
| CN-1057607-C | Double functional chromatographic material and preparing method and use | BOPU BIOLOG TECH CO LTD GUANGZ (CN) | 2000-10-18 | — | — | CN | disclosed |
| CN-1109980-A | Liquid crystal device | CANON KK (JP) | 1995-10-11 | — | — | CN | disclosed |