Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304329 | 0.80 | MAPT (0.43) | ACHEDDB1CRBNSLC6A2SLC6A4 | |
| SCHEMBL10726551 | 0.78 | SMN1; SMN2 (0.42) | DDB1CRBNGAA | |
| SCHEMBL8327879 | 0.78 | SMN1; SMN2 (0.42) | DDB1CRBNGAA | |
| SCHEMBL10298928 | 0.78 | TSHR (0.46) | PTGER2ACHEHSD11B1DDB1CRBN | |
| SCHEMBL9941228 | 0.76 | PTGER2 (0.44) | PTGER2HSD11B1DDB1CRBNSLC6A2 | |
| SCHEMBL10006223 | 0.71 | PTGER2 (0.40) | PTGER2HSD11B1SLC6A2TP53PTGER3 | |
| SCHEMBL9939438 | 0.70 | PTGER2 (0.47) | PTGER2SLC6A2GAA | |
| SCHEMBL4607515 | 0.70 | SLC6A2 (0.41) | PTGER2ACHEDDB1CRBNSLC6A2 | |
| SCHEMBL9308995 | 0.69 | ESR2 (0.58) | PTGER2ACHEDDB1CRBNSLC6A2 | |
| SCHEMBL22201150 | 0.69 | DDB1 (0.47) | PTGER2HSD11B1DDB1CRBNSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259977-A2 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-16 | — | — | EP | disclosed |