Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.64 |
| ▸ | CES1 | P23141 | 10/20 | 0.64 |
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371814 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL2222667 | 1.00 | FAAH (0.64) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL23896902 | 0.92 | SLC22A6 (0.58) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3440264 | 0.81 | LMNA (0.53) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL7393724 | 0.80 | FAAH (0.64) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL31152148 | 0.78 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL31636122 | 0.78 | FAAH (0.61) | FAAHCES1CES2MEN1CYP1A2 | |
| Adipic Acid SCHEMBL5475921 | 0.78 | TSHR (1.00) | MEN1KMT2AHSD17B10LMNATSHR | |
| SCHEMBL166746 | 0.78 | TSHR (1.00) | MEN1KMT2AHSD17B10LMNATSHR | |
| SCHEMBL21065467 | 0.78 | TSHR (1.00) | MEN1KMT2AHSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267565-A1 | One-step process for preparing mixed substituted 1,2-diacyl-sn-glycero-3-phosphocholines | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1988-05-18 | — | — | EP | disclosed |