Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | GYS1 | P13807 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945180 | 0.90 | KIF11 (0.45) | KIF11CA3CA6CA5ACA9 | |
| SCHEMBL16179246 | 0.90 | KIF11 (0.45) | KIF11CA3CA6CA5ACA9 | |
| SCHEMBL15850523 | 0.84 | KIF11 (0.44) | KIF11GPR3KDM1A | |
| SCHEMBL18893875 | 0.82 | KIF11 (0.42) | KIF11CA3CA6CA5ACA9 | |
| SCHEMBL31235141 | 0.79 | KIF11 (0.37) | KIF11CA3CA6CA5ACA9 | |
| SCHEMBL1027386 | 0.79 | KIF11 (0.41) | KIF11CA6CA5ACA9CA14 | |
| SCHEMBL319598 | 0.79 | KIF11 (0.41) | KIF11GPR3KDM1AMCL1PTPN7 | |
| SCHEMBL10698070 | 0.79 | TMPRSS4 (0.39) | KIF11CA3CA6CA5ACA9 | |
| SCHEMBL3990912 | 0.79 | KIF11 (0.37) | KIF11CA3CA6CA5ACA9 | |
| SCHEMBL8975074 | 0.78 | KIF11 (0.41) | KIF11GPR3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |