Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340005 | 0.91 | HTR3E (0.42) | TMPRSS4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8975023 | 0.81 | HTR3E (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10697706 | 0.79 | KIF11 (0.45) | KIF11CA3CA6CA5ACA9 | |
| SCHEMBL7272204 | 0.79 | NOTUM (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL23239698 | 0.77 | RAPGEF4 (0.40) | TMPRSS4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31379539 | 0.77 | TMPRSS4 (0.38) | TMPRSS4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1023973 | 0.77 | ALDH1A1 (0.43) | TMPRSS4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL17959909 | 0.77 | TMPRSS4 (0.38) | TMPRSS4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL26772968 | 0.76 | LMNA (0.39) | TMPRSS4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL26649343 | 0.76 | HSD17B10 (0.55) | TSHRHSD17B10HPGDCYP3A4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |