Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463575 | 0.93 | ALDH1A1 (0.61) | TBXA2RMEN1KMT2APRMT1AKR1C3 | |
| SCHEMBL10460469 | 0.90 | TBXA2R (0.66) | TBXA2RMEN1KMT2APRMT1AKR1C3 | |
| SCHEMBL9659280 | 0.88 | TBXA2R (0.70) | TBXA2RMEN1KMT2APRMT1AKR1C3 | |
| SCHEMBL10699471 | 0.88 | CYP1A2 (0.62) | TBXA2RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9718429 | 0.87 | TBXA2R (0.59) | TBXA2RMEN1KMT2APRMT1AKR1C3 | |
| SCHEMBL10461761 | 0.86 | TBXA2R (0.56) | TBXA2RMEN1KMT2APRMT1AKR1C3 | |
| SCHEMBL10462267 | 0.85 | TBXA2R (0.67) | TBXA2RMEN1KMT2APRMT1AKR1C3 | |
| SCHEMBL10461966 | 0.84 | TBXA2R (0.54) | TBXA2RMEN1KMT2APRMT1AKR1C3 | |
| SCHEMBL9130060 | 0.83 | TBXA2R (0.75) | TBXA2RMEN1KMT2APRMT1AKR1C3 | |
| SCHEMBL9754552 | 0.82 | MEN1 (0.84) | TBXA2RMEN1KMT2APRMT1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260527-A2 | Synergetic combination comprising a phosphodiesterase inhibitor and a thromboxan-A2-antagonist, and their use or manufacture | Dr. Karl Thomae GmbH (DE) | 1988-03-23 | — | — | EP | disclosed |