Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461761 | 0.90 | TBXA2R (0.56) | TBXA2RTBXAS1MEN1KMT2APRMT1 | |
| SCHEMBL9718385 | 0.89 | ALDH1A1 (0.64) | TBXA2RTBXAS1MEN1KMT2AALDH1A1 | |
| SCHEMBL9718387 | 0.88 | ALDH1A1 (0.62) | TBXA2RTBXAS1MEN1KMT2AALDH1A1 | |
| SCHEMBL9659280 | 0.87 | TBXA2R (0.70) | TBXA2RTBXAS1MEN1KMT2APRMT1 | |
| SCHEMBL10697737 | 0.87 | TBXA2R (0.63) | TBXA2RMEN1KMT2APRMT1ALDH1A1 | |
| SCHEMBL10460469 | 0.84 | TBXA2R (0.66) | TBXA2RTBXAS1MEN1KMT2APRMT1 | |
| SCHEMBL10461595 | 0.84 | ALDH1A1 (0.54) | TBXA2RTBXAS1MEN1KMT2APRMT1 | |
| SCHEMBL10461966 | 0.84 | TBXA2R (0.54) | TBXA2RTBXAS1MEN1KMT2APRMT1 | |
| SCHEMBL10462267 | 0.82 | TBXA2R (0.67) | TBXA2RTBXAS1MEN1KMT2APRMT1 | |
| SCHEMBL9718367 | 0.81 | TBXAS1 (0.58) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260527-B1 | SYNERGETIC COMBINATION COMPRISING A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A2-ANTAGONIST, AND THEIR USE OR MANUFACTURE | Dr. Karl Thomae GmbH (DE) | 1992-04-01 | — | — | EP | disclosed |
| EP-0194548-A2 | Sulfonylaminoethyl compounds, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1986-09-17 | — | — | EP | disclosed |