Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413098 | 1.00 | HCAR2 (0.43) | HCAR2TSHRADRA1APDE4DCA12 | |
| SCHEMBL10413099 | 1.00 | HCAR2 (0.43) | HCAR2TSHRADRA1APDE4DCA12 | |
| SCHEMBL4449233 | 0.79 | TSHR (0.42) | HCAR2TSHRADRA1APDE4DCA12 | |
| SCHEMBL4449226 | 0.79 | TSHR (0.42) | HCAR2TSHRADRA1APDE4DCA12 | |
| SCHEMBL11494167 | 0.77 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| SCHEMBL11494163 | 0.77 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| Hydrochloric Acid SCHEMBL22400629 | 0.77 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| SCHEMBL489372 | 0.77 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| SCHEMBL8521397 | 0.77 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| SCHEMBL489374 | 0.77 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274379-A2 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-13 | — | — | EP | disclosed |