Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521397 | 1.00 | HCAR2 (0.46) | HCAR2TSHROPRK1CA12AKR1B10 | |
| SCHEMBL489372 | 1.00 | HCAR2 (0.46) | HCAR2TSHROPRK1CA12AKR1B10 | |
| SCHEMBL6861008 | 0.86 | LMNA (0.38) | HCAR2TSHROPRK1LMNAALOX15 | |
| SCHEMBL11494167 | 0.81 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| Hydrochloric Acid SCHEMBL22400629 | 0.81 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| SCHEMBL11494163 | 0.81 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| SCHEMBL9674283 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL21680864 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL10589861 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL9674276 | 0.80 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939855-B | Process for preparing 1, 4-dihydropyridine derivatives containing azulene ring structure | 马鞍山市泰博化工科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-113317995-B | Dental restoration material for oral science and preparation method thereof | 云南中辉口腔医院有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-113317995-A | Dental restoration material for oral science and preparation method thereof | 宁波因天之序生物科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-112939855-A | Method for preparing 1, 4-dihydropyridine derivative containing azulene ring structure | 马鞍山市泰博化工科技有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-105732484-A | Preparation method of Nimodipine | 青岛市黄岛区中医医院 | 2016-07-06 | — | — | CN | claimed |
| EP-0302980-B1 | 1,4-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DELAGRANGE S.A. (ES) | 1991-03-13 | — | — | EP | claimed |
| EP-0167068-B1 | Isopropyl-2[2-(3-trifluoromethylphenoxy)ethyl]ester of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylic acid, process for its preparation, and its use as a medicine | BAYER AG (DE) | 1990-02-28 | — | — | EP | claimed |
| CN-119859377-A | Polyacetal resin composition | 旭化成株式会社 | 2025-04-22 | — | — | CN | disclosed |
| CN-117865824-A | Preparation method of nimodipine intermediate | 山东省农药科学研究院 | 2024-04-12 | — | — | CN | disclosed |
| CN-112939855-B | Process for preparing 1, 4-dihydropyridine derivatives containing azulene ring structure | 马鞍山市泰博化工科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-114989072-B | Method for asymmetric catalytic synthesis of chiral 1, 4-dihydropyridine compound and application thereof | 四川大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-114989072-A | Method for asymmetric catalytic synthesis of chiral 1, 4-dihydropyridine compound and application thereof | 四川大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-113317995-B | Dental restoration material for oral science and preparation method thereof | 云南中辉口腔医院有限公司 | 2022-06-07 | — | — | CN | disclosed |
| US-4472411-A | 1,4-Dihydropyridine derivatives and use as vasodilators | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0092936-A1 | 1,4-Dihydropyridine derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-11-02 | — | — | EP | disclosed |
| US-4393070-A | HYPOTENSIVE, VASODILATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4370334-A | VASODILATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-25 | — | — | US | disclosed |
| US-4338322-A | 1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
| US-4307103-A | TREATMENT OF HYPERTENSION AND CARDIOVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |
| US-4284634-A | HYPOTENSIVE VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |