Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521397 | 1.00 | HCAR2 (0.46) | HCAR2TSHROPRK1CA12AKR1B10 | |
| SCHEMBL489374 | 1.00 | HCAR2 (0.46) | HCAR2TSHROPRK1CA12AKR1B10 | |
| SCHEMBL6861008 | 0.86 | LMNA (0.38) | HCAR2TSHROPRK1LMNAALOX15 | |
| SCHEMBL11494167 | 0.81 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| Hydrochloric Acid SCHEMBL22400629 | 0.81 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| SCHEMBL11494163 | 0.81 | HCAR2 (0.46) | HCAR2TSHRCA12AKR1B10CA1 | |
| SCHEMBL9674283 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL21680864 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL10589861 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL9674276 | 0.80 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | claimed |
| CN-113317995-B | Dental restoration material for oral science and preparation method thereof | 云南中辉口腔医院有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-113317995-A | Dental restoration material for oral science and preparation method thereof | 宁波因天之序生物科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| US-7329756-B2 | Process for the manufacture of Isradipine | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2008-02-12 | — | — | US | claimed |
| US-20060167063-A1 | Process for the manufacture of isradipine | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2006-07-27 | — | — | US | claimed |
| WO-2005005437-A1 | AN IMPROVED PROCESS FOR THE MANUFACTURE OF ISRADIPINE. | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2005-01-20 | — | — | WO | claimed |
| EP-0302980-B1 | 1,4-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DELAGRANGE S.A. (ES) | 1991-03-13 | — | — | EP | claimed |
| EP-0167068-B1 | Isopropyl-2[2-(3-trifluoromethylphenoxy)ethyl]ester of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylic acid, process for its preparation, and its use as a medicine | BAYER AG (DE) | 1990-02-28 | — | — | EP | claimed |
| EP-0167068-A2 | Isopropyl-2[2-(3-trifluoromethylphenoxy)ethyl]ester of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylic acid, process for its preparation, and its use as a medicine | BAYER AG (DE) | 1986-01-08 | — | — | EP | claimed |
| CN-121574135-A | Method for synthesizing 7-oxa-2-azabicyclo [3.3.1] non-3-alkene-1-alcohol by rare earth catalysis | 北京化工大学 | 2026-02-27 | — | — | CN | disclosed |
| CN-119859377-A | Polyacetal resin composition | 旭化成株式会社 | 2025-04-22 | — | — | CN | disclosed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | disclosed |
| US-12227479-B2 | Dihydropyridines for the treatment of cognitive impairment or traumatic brain injury | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2025-02-18 | — | — | US | disclosed |
| CN-117865824-A | Preparation method of nimodipine intermediate | 山东省农药科学研究院 | 2024-04-12 | — | — | CN | disclosed |
| EP-0010130-B1 | SILA-SUBSTITUTED 1,4-DIHYDROPYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1981-12-23 | — | — | EP | disclosed |
| US-4307103-A | TREATMENT OF HYPERTENSION AND CARDIOVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |
| EP-0009206-B1 | FLUOR-CONTAINING 1,4-DIHYDROPYRIDINES, PHARMACEUTICALS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1981-10-14 | — | — | EP | disclosed |
| US-4284634-A | HYPOTENSIVE VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| EP-0002208-A1 | Nitro 1,4-dihydropyridines, medicaments containing them and their manufacture | BAYER AG (DE) | 1979-06-13 | — | — | EP | disclosed |
| EP-0001054-A2 | 2-Pyridyl-1,4-dihydropyridine derivatives, methods for their preparation and their pharmaceutical use | BAYER AG (DE) | 1979-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167063-A1 | Process for the manufacture of isradipine | ACMSD, AASDHPPT, DDC | HCAR2 43/4885TSHR 4201/4885OPRK1 542/4885 |
| US-12227479-B2 | Dihydropyridines for the treatment of cognitive impairment or traumatic brain injury | GAP43, SYNJ1, PSD | HCAR2 1682/4885TSHR 4511/4885OPRK1 854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.