Oxalic Acid

Oxalic Acid

SCHEMBL10697790

CCC(N)C1CCCCC1.O=C(O)C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.45
ALDH1A1 P00352 1/20 0.43
EPHX1 P07099 3/20 0.42
MEN1 O00255 1/20 0.38
MITF O75030 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 2/20 0.38
TP53 P04637 1/20 0.38
GRIK1 P39086 1/20 0.38
DPP4 P27487 1/20 0.37
GMNN O75496 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712005 0.87 SHBG (0.56) SHBGALDH1A1EPHX1KDM4ETP53
SCHEMBL5908926 0.87 SHBG (0.56) SHBGALDH1A1EPHX1KDM4ETP53
SCHEMBL25949959 0.87 SHBG (0.56) SHBGALDH1A1EPHX1KDM4ETP53
SCHEMBL23842922 0.87 SHBG (0.56) SHBGALDH1A1EPHX1KDM4ETP53
SCHEMBL29008423 0.87 SHBG (0.56) SHBGALDH1A1EPHX1KDM4ETP53
SCHEMBL23685673 0.87 SHBG (0.56) SHBGALDH1A1EPHX1KDM4ETP53
SCHEMBL2257328 0.87 SHBG (0.56) SHBGALDH1A1EPHX1KDM4ETP53
Hydrochloric Acid SCHEMBL6848858 0.85 SHBG (0.54) SHBGALDH1A1EPHX1KDM4ETP53
Hydrochloric Acid SCHEMBL20302411 0.85 SHBG (0.54) SHBGALDH1A1EPHX1KDM4ETP53
Hydrochloric Acid SCHEMBL1356288 0.85 SHBG (0.54) SHBGALDH1A1EPHX1KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273658-A1 3-Aryloxy-3-substituted propanamines ELI LILLY AND COMPANY (US) 1988-07-06 EP disclosed