SCHEMBL10697862

SCHEMBL10697862

O=C1C=C(c2ccccc2Nc2ccccc2)C(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
LMNA P02545 5/20 0.51
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
ALDH1A1 P00352 5/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
MAPK1 P28482 4/20 0.51
EGFR P00533 3/20 0.51
SRC P12931 3/20 0.51
KDM4E B2RXH2 3/20 0.51
NPSR1 Q6W5P4 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
NFKB1 P19838 2/20 0.51
BLM P54132 2/20 0.51
GLA P06280 2/20 0.51
CYP3A4 P08684 2/20 0.51
HPGD P15428 2/20 0.51
RGS12 O14924 1/20 0.51
GMNN O75496 1/20 0.51
PRKD3 O94806 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3762747 0.83 ALDH1A1 (0.47) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL29588900 0.83 ALDH1A1 (0.47) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL27664385 0.78 GSK3B (0.50) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL121405 0.78 GSK3B (0.50) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL992016 0.77 ALDH1A1 (0.45) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL11120799 0.77 GSK3B (0.48) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL6537555 0.74 PTPN1 (0.44) MAPTLMNAGSK3BCASP3GAA
SCHEMBL3182292 0.74 ALDH1A1 (0.44) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL13363917 0.72 MAPT (0.61) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL87616 0.72 GSK3B (0.47) MAPTLMNAMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240308-A Self-healing polymer pipe and preparation method thereof 攀枝花钢城集团有限公司 2024-06-25 CN claimed
CN-118063870-A High-oxygen-resistance polymer pipe and preparation method thereof 攀枝花钢城集团有限公司 2024-05-24 CN claimed
CN-116874962-A Self-lubricating rubber composition and preparation process thereof 东莞新东方科技有限公司 2023-10-13 CN claimed
CN-114716837-B Waterproof composite modified asphalt and preparation method thereof 苏州三正路面工程有限公司 2023-09-01 CN claimed
CN-113956579-B High-heat-resistant adhesive and preparation method and application thereof 保定三源橡胶有限公司 2023-02-24 CN claimed
CN-114716837-A Waterproof composite modified asphalt and preparation method thereof 苏州三正路面工程有限公司 2022-07-08 CN claimed
CN-111849046-B Semiconductive external shielding material for high-temperature-resistant cable 上海蓝昊电气江苏有限公司 2022-05-06 CN claimed
CN-113956579-A High-heat-resistant adhesive and preparation method and application thereof 保定三源橡胶有限公司 2022-01-21 CN claimed
CN-109096624-B Rubber composition for automobile hose rubber core and preparation method thereof 青岛三祥科技股份有限公司 2021-08-10 CN claimed
CN-108314849-B Rubber composition and processing method thereof, adhesive tape and rubber roller using rubber composition and production method thereof 杭州星庐科技有限公司 2021-05-14 CN claimed
CN-100593603-C Method for increasing water filtering performance of non-asbestos latex sheet UNIV SHAANXI SCIENCE & TECH 2010-03-10 CN claimed
CN-101634121-A Method for preparing asbestos latex sheets UNIV SHAANXI SCIENCE & TECH 2010-01-27 CN claimed
CN-101307161-A High heat-resistant styrene-butadiene rubber composite material as covering layer of conveying belt UNIV BEIJING CHEMICAL (CN) 2008-11-19 CN claimed
CN-101250305-A High heat-resistant rubber composite material for conveyor belt covering UNIV BEIJING CHEMICAL (CN) 2008-08-27 CN claimed
CN-101105021-A Method for increasing water filtering performance of non-asbestos latex sheet UNIV SHANXI SCIENCE & TECH (CN) 2008-01-16 CN claimed
CN-101105022-A Method for preparing non-asbestos latex sheet UNIV SHANXI SCIENCE & TECH (CN) 2008-01-16 CN claimed
CN-100351463-C Method for improving water filtering performance of asbestos latex sheet UNIV SHAANXI SCI & TECH (CN) 2007-11-28 CN claimed
CN-100351462-C Preparation method of asbestos latex sheet UNIV SHAANXI SCI & TECH (CN) 2007-11-28 CN claimed
CN-1707021-A Method for improving water filtering performance of asbestos and non-asbestos latex sheet UNIV SHAANXI SCI & TECH (CN) 2005-12-14 CN claimed
CN-1707020-A Method for preparing asbestos and non-asbestos latex sheet UNIV SHAANXI SCI & TECH (CN) 2005-12-14 CN claimed