Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149422 | 0.83 | MCL1 (0.46) | MCL1AKR1C3ALDH1A1AKR1C1MEN1 | |
| SCHEMBL7149424 | 0.83 | MCL1 (0.46) | MCL1AKR1C3ALDH1A1AKR1C1MEN1 | |
| SCHEMBL7672337 | 0.73 | ABCG2 (0.51) | MCL1AKR1C3ALDH1A1AKR1C1MEN1 | |
| SCHEMBL20596721 | 0.72 | MCL1 (0.45) | MCL1AKR1C3ALDH1A1MAPTLMNA | |
| SCHEMBL10436436 | 0.71 | MCL1 (0.47) | MCL1AKR1C3ALDH1A1MAPTAKR1C1 | |
| SCHEMBL5488316 | 0.70 | MCL1 (0.46) | MCL1AKR1C3ALDH1A1MAPTLMNA | |
| SCHEMBL4649011 | 0.69 | AKR1C3 (0.47) | MCL1AKR1C3ALDH1A1MAPTLMNA | |
| SCHEMBL4649014 | 0.69 | AKR1C3 (0.47) | MCL1AKR1C3ALDH1A1MAPTLMNA | |
| SCHEMBL6510379 | 0.69 | MCL1 (0.49) | MCL1AKR1C3ALDH1A1AKR1C1MEN1 | |
| SCHEMBL7564827 | 0.69 | MCL1 (0.49) | MCL1AKR1C3ALDH1A1AKR1C1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274546-A1 | New oxazolinone compounds useful as intermediates for the preparation of insecticidal and acaracidal cinnamide compounds | AMERICAN CYANAMID COMPANY (US) | 1988-07-20 | — | — | EP | disclosed |