Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17146607 | 0.87 | KDM4E (0.57) | TDP1KDM4ELMNAMAPTHTT | |
| SCHEMBL17174066 | 0.87 | KDM4E (0.57) | TDP1KDM4ELMNAMAPTHTT | |
| SCHEMBL599374 | 0.84 | LMNA (0.67) | TDP1KDM4ELMNAMAPTHTT | |
| SCHEMBL17146614 | 0.83 | KDM4E (0.53) | TDP1KDM4ELMNAMAPTHTT | |
| SCHEMBL10032468 | 0.82 | LMNA (0.64) | TDP1KDM4ELMNAMAPTHTT | |
| SCHEMBL29888960 | 0.82 | LMNA (0.64) | TDP1KDM4ELMNAMAPTHTT | |
| SCHEMBL17174089 | 0.82 | ALDH1A1 (0.43) | TDP1KDM4ELMNAMAPTHTT | |
| Phenanthroline SCHEMBL29101071 | 0.81 | SMN1; SMN2 (0.73) | TDP1KDM4ELMNAMAPTHTT | |
| SCHEMBL17174069 | 0.81 | KDM4E (0.47) | TDP1KDM4ELMNAMAPTHTT | |
| Phenanthroline SCHEMBL23152699 | 0.80 | TDP1 (1.00) | TDP1KDM4ELMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254202-A1 | Method of preparing integral multilayer analytical element | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |