Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565087 | 0.82 | TSHR (0.41) | HTTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10696369 | 0.80 | MEN1 (0.41) | HTTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5858419 | 0.80 | MEN1 (0.41) | HTTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10696689 | 0.78 | MEN1 (0.35) | HTTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11883483 | 0.77 | TAAR1 (0.47) | LMNASMN1; SMN2GLATSHR | |
| SCHEMBL4258677 | 0.75 | ALDH1A1 (0.34) | HTTKMT2AMEN1ALDH1A1LMNA | |
| Isopropyldiphenylamine SCHEMBL2119060 | 0.72 | ALDH1A1 (0.50) | HTTKMT2AMEN1ALDH1A1LMNA | |
| Isopropyldiphenylamine SCHEMBL2119054 | 0.72 | ALDH1A1 (0.50) | HTTKMT2AMEN1ALDH1A1LMNA | |
| Isopropyldiphenylamine SCHEMBL27697074 | 0.72 | ALDH1A1 (0.50) | HTTKMT2AMEN1ALDH1A1LMNA | |
| Isopropyldiphenylamine SCHEMBL31410717 | 0.70 | ALDH1A1 (0.49) | HTTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |