Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697965 | 0.78 | HTT (0.38) | MEN1HTTKMT2AALDH1A1LMNA | |
| SCHEMBL5858419 | 0.77 | MEN1 (0.41) | MEN1HTTKMT2AALDH1A1LMNA | |
| SCHEMBL10696369 | 0.77 | MEN1 (0.41) | MEN1HTTKMT2AALDH1A1LMNA | |
| SCHEMBL7372396 | 0.75 | AOC3 (0.40) | MEN1HTTKMT2AAOC3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6287950 | 0.73 | AOC3 (0.39) | MEN1HTTKMT2AAOC3ALDH1A1 | |
| SCHEMBL4258677 | 0.72 | ALDH1A1 (0.34) | MEN1HTTKMT2AALDH1A1LMNA | |
| SCHEMBL4852028 | 0.71 | AOC3 (0.45) | AOC3ALDH1A1LMNAALOX5KDM4E | |
| SCHEMBL1983878 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2AAOC3ALDH1A1LMNA | |
| SCHEMBL28882359 | 0.71 | ALDH1A1 (0.37) | MEN1HTTKMT2AAOC3ALDH1A1 | |
| SCHEMBL2721666 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2AAOC3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |