Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700833 | 1.00 | PRSS1 (0.45) | PRSS1TMPRSS6F2PRSS2PRSS3 | |
| SCHEMBL10698745 | 0.99 | POLB (0.46) | PRSS1TMPRSS6F2PRSS2PRSS3 | |
| SCHEMBL10702473 | 0.94 | POLB (0.47) | PRSS1TMPRSS6F2PRSS2PRSS3 | |
| SCHEMBL9809366 | 0.88 | POLB (0.49) | TMPRSS6F2POLBLMNASCN5A | |
| SCHEMBL28718042 | 0.87 | TDP1 (0.49) | PRSS1TMPRSS6F2PRSS2PRSS3 | |
| SCHEMBL1206152 | 0.82 | CA1 (0.49) | TMPRSS6F2POLBLMNACA1 | |
| SCHEMBL10699417 | 0.81 | SCN5A (0.46) | TMPRSS6F2POLBLMNASCN5A | |
| SCHEMBL22661373 | 0.81 | POLB (0.50) | TMPRSS6F2POLBLMNASCN5A | |
| SCHEMBL11934949 | 0.79 | PRSS1 (0.53) | PRSS1TMPRSS6F2PRSS2PRSS3 | |
| SCHEMBL11935689 | 0.79 | PRSS1 (0.46) | PRSS1TMPRSS6F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284413-A2 | Derivative of a fibrinolytic enzyme | BEECHAM GROUP PLC (GB) | 1988-09-28 | — | — | EP | disclosed |