Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697987 | 0.99 | PRSS1 (0.45) | POLBLMNASCN5ACYP1A2MAOA | |
| SCHEMBL10700833 | 0.99 | PRSS1 (0.45) | POLBLMNASCN5ACYP1A2MAOA | |
| SCHEMBL10702473 | 0.96 | POLB (0.47) | POLBLMNASCN5ACYP1A2MAOA | |
| SCHEMBL9809366 | 0.90 | POLB (0.49) | POLBLMNASCN5ACYP1A2MAOA | |
| SCHEMBL28718042 | 0.86 | TDP1 (0.49) | POLBLMNASCN5ACYP1A2MAOA | |
| SCHEMBL1206152 | 0.83 | CA1 (0.49) | POLBLMNACA1CA2CA12 | |
| SCHEMBL10699417 | 0.82 | SCN5A (0.46) | POLBLMNASCN5ACYP1A2MAOA | |
| SCHEMBL22661373 | 0.82 | POLB (0.50) | POLBLMNASCN5ACYP1A2MAOA | |
| SCHEMBL22940491 | 0.79 | POLB (0.72) | POLBLMNASCN5ACYP1A2MAOA | |
| SCHEMBL23619645 | 0.79 | CA1 (0.47) | POLBLMNAMAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284413-A2 | Derivative of a fibrinolytic enzyme | BEECHAM GROUP PLC (GB) | 1988-09-28 | — | — | EP | disclosed |