Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986088 | 0.76 | TAAR1 (0.46) | TAAR1HTR2AHRH1DPP4F2 | |
| SCHEMBL9205893 | 0.76 | TAAR1 (0.52) | TAAR1HTR2AHRH1CHRNB2CHRNA4 | |
| SCHEMBL8974394 | 0.75 | LMNA (0.44) | TAAR1HTR2AHRH1DPP4 | |
| SCHEMBL8710872 | 0.73 | MAOB (0.50) | TAAR1HTR2ASLC6A4SLC6A3 | |
| SCHEMBL4682442 | 0.72 | TAAR1 (0.42) | TAAR1HTR2AHRH1DPP4CHRNB2 | |
| SCHEMBL5787394 | 0.72 | TAAR1 (0.42) | TAAR1HTR2AHRH1DPP4CHRNB2 | |
| SCHEMBL4820232 | 0.70 | KCNH2 (0.41) | TAAR1HTR2ALOXL2CYP2D6 | |
| SCHEMBL8522965 | 0.69 | DPP4 (0.45) | TAAR1HTR2AHRH1DPP4F2 | |
| SCHEMBL7755851 | 0.68 | HTR2A (0.54) | TAAR1HTR2AHRH1DPP4F2 | |
| SCHEMBL149259 | 0.67 | HTR2A (1.00) | TAAR1HTR2AHRH1DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278089-A2 | 2-Azacyclocarboxamide derivatives | FISONS CORPORATION (a Massachusetts corporation) (US) | 1988-08-17 | — | — | EP | disclosed |