SCHEMBL8710872

SCHEMBL8710872

[CH](Cc1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
MAPK1 P28482 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ARG2 P78540 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CALM1 P0DP23 1/20 0.38
HTR2A P28223 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
EPHX1 P07099 2/20 0.36
MRGPRX1 Q96LB2 1/20 0.36
ACP3 P15309 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
KCNH2 Q12809 1/20 0.35
IDO1 P14902 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4820232 0.77 KCNH2 (0.41) HTR2ATAAR1SMN1; SMN2ACP3SIGMAR1
SCHEMBL794180 0.77 MAOB (0.46) MAOBMAPK1SLC6A2SLC6A4SLC6A3
SCHEMBL8817971 0.77 MAOB (0.46) MAOBMAPK1SLC6A2SLC6A4SLC6A3
SCHEMBL9226100 0.76 MAOB (0.44) MAOBMAPK1SLC6A2SLC6A4SLC6A3
SCHEMBL6982117 0.76 MAPK1 (0.41) MAOBMAPK1SMN1; SMN2SIGMAR1KCNH2
SCHEMBL11498274 0.74 MAOB (0.43) MAOBMAPK1CA1CA2ARG2
SCHEMBL11967590 0.74 MAOB (0.43) MAOBMAPK1SIGMAR1KCNH2TP53
SCHEMBL10698044 0.73 TAAR1 (0.50) SLC6A4SLC6A3HTR2ATAAR1
SCHEMBL1289345 0.73 MAOB (0.52) MAOBCA1CA2ARG2SLC6A2
SCHEMBL8974394 0.73 LMNA (0.44) HTR2ATAAR1SIGMAR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118178688-A CT contrast agent for detection of cachexia 日内瓦大学 2024-06-14 CN disclosed
CN-118202020-A Emulsion, composition for emulsion, method for producing emulsion, and use of emulsion 艾迪珀斯股份公司 2024-06-14 CN disclosed
WO-1998024785-A1 INDOLE-UREA DERIVATIVES WITH 5-HT ANTAGONIST PROPERTIES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-06-11 WO disclosed
US-4430425-A HYDROQUINONE DERIVATIVES CIBA-GEIGY AG (CH) 1984-02-07 US disclosed
EP-0069070-A1 Colour photographic materials containing stabilizers CIBA-GEIGY AG (CH) 1983-01-05 EP disclosed