Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697675 | 0.92 | HRH3 (0.42) | MEN1KMT2AHRH3SLC6A4ESRRB | |
| SCHEMBL9857099 | 0.85 | ESR1 (0.52) | MEN1KMT2ASLC6A4GBA1PSMB1 | |
| SCHEMBL9857608 | 0.85 | ESR1 (0.52) | MEN1KMT2ASLC6A4GBA1PSMB1 | |
| SCHEMBL10698397 | 0.83 | GBA1 (0.41) | MEN1KMT2AHRH3SLC6A4GBA1 | |
| SCHEMBL10698635 | 0.78 | ESRRB (0.52) | MEN1KMT2AESRRBLMNAESR1 | |
| SCHEMBL10696281 | 0.78 | ESRRB (0.52) | MEN1KMT2AESRRBLMNAESR1 | |
| SCHEMBL9857875 | 0.74 | ESR1 (0.53) | MEN1KMT2ASLC6A4GBA1PSMB1 | |
| SCHEMBL9857866 | 0.72 | ESR1 (0.62) | MEN1KMT2ASLC6A4GBA1PSMB1 | |
| SCHEMBL9857160 | 0.72 | ESR1 (0.62) | MEN1KMT2ASLC6A4GBA1PSMB1 | |
| SCHEMBL2710225 | 0.71 | CYP2D6 (0.55) | MEN1KMT2ASLC6A4GBA1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272330-A1 | 1,1,2-TRIARYL-1-BUTENE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-06-29 | — | — | EP | disclosed |