Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | ESRRG | P62508 | 5/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698084 | 0.92 | MEN1 (0.39) | HRH3SLC6A4ESRRBESR1MEN1 | |
| SCHEMBL9857875 | 0.82 | ESR1 (0.53) | SLC6A4ESRRGESRRBESR1HDAC6 | |
| SCHEMBL28421381 | 0.78 | ESRRG (0.53) | SLC6A4ESRRGESRRBESR1MEN1 | |
| SCHEMBL9857099 | 0.77 | ESR1 (0.52) | SLC6A4ESRRGESRRBESR1HDAC6 | |
| SCHEMBL9857608 | 0.77 | ESR1 (0.52) | SLC6A4ESRRGESRRBESR1HDAC6 | |
| SCHEMBL10698397 | 0.75 | GBA1 (0.41) | HRH3SLC6A4ESRRGESRRBESR1 | |
| SCHEMBL11112652 | 0.73 | CHRNB2 (0.48) | SLC6A4ESRRGESRRBESR1MEN1 | |
| SCHEMBL2710225 | 0.70 | CYP2D6 (0.55) | SLC6A4ESRRGESRRBESR1MEN1 | |
| SCHEMBL7929087 | 0.70 | CYP2D6 (0.55) | SLC6A4ESRRGESRRBESR1MEN1 | |
| SCHEMBL8732737 | 0.70 | CYP2D6 (0.55) | SLC6A4ESRRGESRRBESR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272330-A1 | 1,1,2-TRIARYL-1-BUTENE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-06-29 | — | — | EP | disclosed |