Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12860038 | 0.93 | THRB (0.50) | ALDH1A1THRBTSHRSLC29A1DRD3 | |
| SCHEMBL235038 | 0.93 | THRB (0.50) | ALDH1A1THRBTSHRSLC29A1DRD3 | |
| SCHEMBL3190974 | 0.88 | THRB (0.46) | ALDH1A1THRBTSHRSLC29A1DRD3 | |
| SCHEMBL22838359 | 0.86 | THRB (0.49) | ALDH1A1THRBTSHRSLC29A1SLC18A3 | |
| SCHEMBL68168 | 0.86 | THRB (0.47) | ALDH1A1THRBTSHRDRD3HRH2 | |
| SCHEMBL22852458 | 0.85 | THRB (0.43) | ALDH1A1THRBTSHRSLC29A1DRD3 | |
| SCHEMBL21274378 | 0.84 | KMT2A (0.46) | ALDH1A1THRBTSHRPOLB | |
| SCHEMBL881770 | 0.84 | KMT2A (0.46) | ALDH1A1THRBTSHRPOLB | |
| SCHEMBL68651 | 0.84 | KMT2A (0.46) | ALDH1A1THRBTSHRPOLB | |
| Bromide SCHEMBL10788752 | 0.83 | KMT2A (0.45) | ALDH1A1THRBTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265091-A1 | Group transfer polymerization and initiators therefor | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |