Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12860038 | 0.94 | THRB (0.50) | THRBALDH1A1TSHRHRH3PAOX | |
| SCHEMBL235038 | 0.94 | THRB (0.50) | THRBALDH1A1TSHRHRH3PAOX | |
| SCHEMBL9292703 | 0.90 | TSHR (0.50) | THRBALDH1A1TSHRHRH3PAOX | |
| SCHEMBL10698103 | 0.88 | ALDH1A1 (0.52) | THRBALDH1A1TSHRHRH3SLC29A1 | |
| SCHEMBL22838359 | 0.88 | THRB (0.49) | THRBALDH1A1TSHRSLC29A1KDM4E | |
| SCHEMBL68168 | 0.87 | THRB (0.47) | THRBALDH1A1TSHRHRH3HTR1B | |
| SCHEMBL25561203 | 0.87 | TSHR (0.56) | THRBALDH1A1TSHRHRH3PAOX | |
| SCHEMBL22852458 | 0.86 | THRB (0.43) | THRBALDH1A1TSHRHRH3PAOX | |
| SCHEMBL21274378 | 0.86 | KMT2A (0.46) | THRBALDH1A1TSHRKDM4EPOLB | |
| SCHEMBL68651 | 0.86 | KMT2A (0.46) | THRBALDH1A1TSHRKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096033-A1 | PLATE-SHAPED WORKPIECE, METHOD, AND SYSTEM FOR THE PRODUCTION THEREOF, AND LACQUER COMPOSITION | FRIEDRICH KLUMPP GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |
| EP-3326834-A1 | PLATE-SHAPED WORKPIECE, METHOD AND SYSTEM FOR THE PRODUCTION OF SAME, AND VARNISH COMPOSITION | Friedrich Klumpp GmbH (DE) | 2018-05-30 | — | — | EP | disclosed |
| US-9758606-B2 | Cyclopropenium polymers and methods for making the same | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-09-12 | — | — | US | disclosed |
| US-20150175727-A1 | CYCLOPROPENIUM POLYMERS AND METHODS FOR MAKING THE SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2015-06-25 | — | — | US | disclosed |
| US-7659324-B2 | Accelerators and initiators, both with polymerizable groups, can be cured without problems by radical polymerization, materials being obtained which contain an extremely small proportion of soluble components | IVOCLAR VIVADENT AG (LI) | 2010-02-09 | — | — | US | disclosed |
| US-7659324-B2 | Accelerators and initiators, both with polymerizable groups, can be cured without problems by radical polymerization, materials being obtained which contain an extremely small proportion of soluble components | IVOCLAR VIVADENT AG (LI) | 2010-02-09 | — | — | US | disclosed |
| US-7659324-B2 | Accelerators and initiators, both with polymerizable groups, can be cured without problems by radical polymerization, materials being obtained which contain an extremely small proportion of soluble components | IVOCLAR VIVADENT AG (LI) | 2010-02-09 | — | — | US | disclosed |
| EP-1574524-B1 | Dental material with improved compatibility | IVOCLAR VIVADENT AG (LI) | 2008-10-08 | — | — | EP | disclosed |
| US-20070166250-A1 | COSMETIC POLYMER COMPOSITION AND COSMETIC | MITSUBISHI CHEMICAL CORPORATION | 2007-07-19 | — | — | US | disclosed |
| US-20050203199-A1 | Dental materials with improved compatibility | IVOCLAR VIVADENT AG | 2005-09-15 | — | — | US | disclosed |
| EP-1574524-A1 | Dental material with improved compatibility | Ivoclar Vivadent AG (LI) | 2005-09-14 | — | — | EP | disclosed |
| US-20040223933-A1 | Cosmetic polymer composition and cosmetic | MITSUBISHI CHEMICAL CORPORATION | 2004-11-11 | — | — | US | disclosed |
| EP-1440680-A1 | COSMETIC POLYMER COMPOSITION AND COSMETIC | Mitsubishi Chemical Corporation (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6375932-B1 | Hair cosmetic composition containing amine-oxide polymer | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6123933-A | A HAIR COSMETIC COMPRISING AN AMINE-OXIDE CONTAINING WATER-SOLUBLE RESIN, PROVIDES GOOD HAIR CONDITIONING PROPERTY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0754444-B1 | Hair cosmetic compositions | MITSUBISHI CHEM CORP (JP) | 1998-05-27 | — | — | EP | disclosed |
| EP-0754444-A2 | Hair cosmetic compositions | Mitsubishi Chemical Corporation (JP) | 1997-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166250-A1 | COSMETIC POLYMER COMPOSITION AND COSMETIC | ERCC1, PCNA, CUTA | THRB 2581/4885ALDH1A1 1048/4885TSHR 3606/4885 |
| US-20040223933-A1 | Cosmetic polymer composition and cosmetic | PCNA, ERCC1, CUTA | THRB 2269/4885ALDH1A1 1133/4885TSHR 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.