Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158244 | 0.86 | PPARA (0.39) | FFAR4DHFRCNR1CNR2CYSLTR2 | |
| SCHEMBL11771086 | 0.83 | DHFR (0.53) | DHFRMEN1KMT2A | |
| SCHEMBL234440 | 0.82 | DHFR (0.54) | DHFRCNR1CNR2MEN1KMT2A | |
| SCHEMBL3189000 | 0.81 | DHFR (0.55) | DHFRMEN1KMT2A | |
| SCHEMBL2754758 | 0.80 | DHFR (0.44) | DHFR | |
| SCHEMBL9329213 | 0.78 | DHFR (0.57) | DHFR | |
| SCHEMBL29646513 | 0.78 | DHFR (0.57) | DHFRCYSLTR1MEN1KMT2A | |
| SCHEMBL13140896 | 0.78 | DHFR (0.57) | DHFRCYSLTR1MEN1KMT2A | |
| SCHEMBL10830967 | 0.77 | DHFR (0.49) | DHFRMEN1KMT2A | |
| SCHEMBL11769332 | 0.77 | DHFR (0.56) | DHFRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271287-A2 | Quinoline dioic acids and amides | MERCK FROSST CANADA INC. (CA) | 1988-06-15 | — | — | EP | disclosed |