Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10223639 | 0.81 | POLQ (0.46) | MAPT | |
| SCHEMBL28835036 | 0.80 | ALDH1A1 (0.59) | POLBNPC1RAB9AALDH1A1HTT | |
| SCHEMBL8245878 | 0.76 | NPC1 (0.64) | SMN1; SMN2ESR1ESR2POLBNPC1 | |
| SCHEMBL5319072 | 0.74 | ESR1 (0.43) | SMN1; SMN2ESR1ESR2POLBNPC1 | |
| SCHEMBL8242543 | 0.74 | HTT (0.42) | ESR1ESR2POLBNPC1RAB9A | |
| SCHEMBL10698132 | 0.73 | POLB (0.39) | SMN1; SMN2ESR1ESR2POLBNPC1 | |
| SCHEMBL5031160 | 0.73 | ALDH1A1 (0.42) | ESR1ESR2POLBNPC1RAB9A | |
| SCHEMBL7813644 | 0.73 | MEN1 (0.50) | POLBNPC1RAB9AALDH1A1HTT | |
| SCHEMBL10364096 | 0.72 | HDAC3 (0.44) | ESR1ESR2ALDH1A1 | |
| SCHEMBL8243336 | 0.70 | ALDH1A1 (0.41) | SMN1; SMN2POLBALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256909-A1 | N,N-bis-(4-fluorophenyl) carbamoyl acetohydroxamic acid and pharmaceutical composition containing it | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1988-02-24 | — | — | EP | disclosed |