Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 4/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698657 | 0.88 | GBA1 (0.38) | ESRRBHRH3DRD2DRD3KEAP1 | |
| SCHEMBL10780217 | 0.78 | LTA4H (0.58) | ESRRGESRRBHRH3DRD2DRD3 | |
| SCHEMBL7152772 | 0.78 | LTA4H (0.58) | ESRRGESRRBHRH3DRD2DRD3 | |
| SCHEMBL7807866 | 0.78 | CYP2D6 (0.51) | ESRRGESRRBDRD2DRD3BCHE | |
| SCHEMBL11567088 | 0.77 | ESR1 (0.50) | ESRRGESRRBHRH3KEAP1NFE2L2 | |
| SCHEMBL7809033 | 0.77 | ESR1 (0.53) | ESRRGESRRBHRH3KEAP1NFE2L2 | |
| SCHEMBL11564379 | 0.76 | ESR1 (0.49) | ESRRGESRRBHRH3KEAP1NFE2L2 | |
| SCHEMBL9857672 | 0.76 | ESR1 (0.63) | ESRRGESRRBDRD2DRD3CYP2D6 | |
| SCHEMBL7809032 | 0.76 | LTA4H (0.52) | ESRRGDRD2DRD3BCHEACHE | |
| SCHEMBL9857681 | 0.76 | ESR1 (0.63) | ESRRGESRRBDRD2DRD3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272330-A1 | 1,1,2-TRIARYL-1-BUTENE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-06-29 | — | — | EP | disclosed |