Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ESRRB | O95718 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698214 | 0.88 | ESRRG (0.40) | HRH3DRD2DRD3KEAP1NFE2L2 | |
| SCHEMBL3137605 | 0.87 | ESR1 (0.47) | RXRARXRBHRH3ESRRBESR1 | |
| Hydrochloric Acid SCHEMBL10698160 | 0.86 | ESR1 (0.47) | ESRRBESR1ESR2LMNAALDH1A1 | |
| SCHEMBL10700049 | 0.81 | CYP2D6 (0.41) | GBA1RXRARXRBHRH3DRD2 | |
| SCHEMBL10698397 | 0.79 | GBA1 (0.41) | GBA1RXRARXRBHRH3DRD2 | |
| SCHEMBL2087896 | 0.77 | ESR1 (0.61) | GBA1DRD2DRD3CYP2D6ESRRB | |
| SCHEMBL8915491 | 0.77 | ESR1 (0.61) | GBA1DRD2DRD3CYP2D6ESRRB | |
| SCHEMBL3781211 | 0.77 | ESR1 (0.61) | GBA1DRD2DRD3CYP2D6ESRRB | |
| SCHEMBL7152772 | 0.77 | LTA4H (0.58) | GBA1HRH3DRD2DRD3KEAP1 | |
| SCHEMBL10780217 | 0.77 | LTA4H (0.58) | GBA1HRH3DRD2DRD3KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272330-A1 | 1,1,2-TRIARYL-1-BUTENE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-06-29 | — | — | EP | disclosed |