Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.31 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694293 | 0.89 | MAOA (0.37) | PGK1PGK2MAOASHBGESR1 | |
| SCHEMBL25328308 | 0.84 | MAOA (0.38) | PGK1PGK2MAOAESR1ESR2 | |
| SCHEMBL30523803 | 0.78 | KDM4E (0.40) | PGK1PGK2MAOAESR1ESR2 | |
| SCHEMBL25329204 | 0.78 | ESR1 (0.40) | MAOASHBGESR1ESR2HMGB1 | |
| SCHEMBL31092527 | 0.78 | ESR1 (0.40) | PGK1PGK2MAOASHBGESR1 | |
| SCHEMBL25328044 | 0.78 | KDM4E (0.40) | PGK1PGK2MAOAESR1ESR2 | |
| SCHEMBL25328523 | 0.78 | ESR1 (0.40) | PGK1PGK2MAOASHBGESR1 | |
| SCHEMBL30523835 | 0.78 | ESR1 (0.40) | MAOASHBGESR1ESR2HMGB1 | |
| SCHEMBL69546 | 0.78 | CA1 (0.42) | PGK1PGK2SHBGESR1ESR2 | |
| SCHEMBL31092524 | 0.78 | ESR1 (0.43) | PGK1PGK2SHBGESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273864-A2 | Diphenylmethanes | CIBA-GEIGY AG (CH) | 1988-07-06 | — | — | EP | disclosed |