SCHEMBL10694293

SCHEMBL10694293

CCc1cc(C)c(Cc2c(C)cc(CC)c(O)c2C)c(C)c1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
NQO1 P15559 2/20 0.36
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
CYP3A4 P08684 3/20 0.35
CYP2C19 P33261 2/20 0.35
LMNA P02545 2/20 0.35
HTR1A P08908 2/20 0.35
ADRA2A P08913 2/20 0.35
CYP1A2 P05177 2/20 0.35
KDM4E B2RXH2 2/20 0.35
GLA P06280 2/20 0.35
GAA P10253 2/20 0.35
MEN1 O00255 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10698224 0.89 PGK1 (0.33) MAOAGABRA1GABRB2NQO1PGK1
SCHEMBL25328308 0.89 MAOA (0.38) MAOAGABRA1GABRB2PGK1PGK2
SCHEMBL28042781 0.84 LDHA (0.42) MAOAGABRA1GABRB2PGK1PGK2
SCHEMBL31092533 0.80 GABRA1 (0.41) MAOAGABRA1GABRB2CYP3A4CYP1A2
SCHEMBL24672233 0.80 GABRA1 (0.41) MAOAGABRA1GABRB2CYP3A4CYP1A2
SCHEMBL15714292 0.80 ESR1 (0.41) MAOAGABRA1GABRB2CYP3A4LMNA
SCHEMBL25328044 0.78 KDM4E (0.40) MAOAGABRA1GABRB2PGK1PGK2
SCHEMBL19927817 0.78 KDM4E (0.40) MAOAGABRA1GABRB2PGK1PGK2
SCHEMBL25329046 0.78 GABRA1 (0.39) MAOAGABRA1GABRB2CYP3A4CYP1A2
SCHEMBL30523803 0.78 KDM4E (0.40) MAOAGABRA1GABRB2PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273864-A2 Diphenylmethanes CIBA-GEIGY AG (CH) 1988-07-06 EP disclosed