Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098780 | 0.84 | ALDH1A1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8107586 | 0.84 | ALDH1A1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8098779 | 0.84 | ALDH1A1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL7806688 | 0.83 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10699439 | 0.83 | TDP1 (0.39) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9519946 | 0.83 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8107960 | 0.83 | ALDH1A1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8957551 | 0.83 | ALDH1A1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8107959 | 0.83 | ALDH1A1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10858260 | 0.82 | DPP8 (0.41) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |