Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521309 | 0.91 | ALDH1A1 (0.39) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9522436 | 0.87 | TDP1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9520280 | 0.86 | PREP (0.50) | PREPPOLB | |
| SCHEMBL10698245 | 0.83 | TDP1 (0.42) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10858260 | 0.82 | DPP8 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10699226 | 0.81 | ALDH1A1 (0.40) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10697655 | 0.81 | TDP1 (0.40) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9794983 | 0.80 | ALDH1A1 (0.39) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL7806688 | 0.80 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10699439 | 0.80 | TDP1 (0.39) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0272456-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4983596-A | Microbiocides; for treatment of infectious diseases | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4963543-A | BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0341557-A1 | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |
| US-4822787-A | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid compounds and antimicrobial activity thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |
| EP-0272456-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |