Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 5/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586593 | 0.90 | KCNH2 (0.81) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL10586588 | 0.90 | KCNH2 (0.81) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL10698327 | 0.85 | KCNH2 (0.54) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL8554680 | 0.85 | KCNH2 (0.79) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL8118056 | 0.85 | KCNH2 (0.72) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL8102541 | 0.85 | KCNH2 (0.72) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL8112102 | 0.84 | KCNH2 (0.69) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL9584977 | 0.84 | KCNH2 (0.71) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL8111734 | 0.84 | KCNH2 (0.71) | KCNH2HRH3MEN1KMT2AKDM4E | |
| SCHEMBL8556904 | 0.84 | KCNH2 (0.71) | KCNH2HRH3MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276700-A1 | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |