Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500961 | 0.93 | KCNH2 (0.52) | KCNH2HRH3MEN1KMT2APOLB | |
| SCHEMBL5279366 | 0.92 | KCNH2 (0.48) | KCNH2HRH3MEN1KMT2APOLB | |
| SCHEMBL9502081 | 0.89 | KCNH2 (0.66) | KCNH2HRH3MEN1KMT2APOLB | |
| SCHEMBL10817831 | 0.85 | KDM4E (0.54) | KCNH2HRH3MEN1KMT2APOLB | |
| SCHEMBL9501126 | 0.85 | KDM4E (0.56) | KCNH2HRH3POLBKDM4EALDH1A1 | |
| SCHEMBL9502534 | 0.85 | KCNH2 (0.69) | KCNH2HRH3MEN1KMT2APOLB | |
| SCHEMBL9502038 | 0.85 | KCNH2 (0.69) | KCNH2HRH3MEN1KMT2APOLB | |
| SCHEMBL9503656 | 0.84 | KCNH2 (0.62) | KCNH2HRH3MEN1KMT2APOLB | |
| SCHEMBL10683412 | 0.84 | KCNH2 (0.47) | KCNH2HRH3MEN1KMT2APOLB | |
| SCHEMBL10698327 | 0.83 | KCNH2 (0.54) | KCNH2HRH3MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312085-B1 | NOVEL QUINOLINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND ANTIBACTERIAL AGENT CONTAINING THEM | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | claimed |