Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645952 | 0.87 | ALOX5 (0.70) | ALOX5 | |
| SCHEMBL9646895 | 0.81 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL31667227 | 0.78 | MEN1 (0.61) | ALOX5 | |
| SCHEMBL9647752 | 0.77 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9645961 | 0.76 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL9596545 | 0.75 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9646598 | 0.75 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9646928 | 0.75 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL22075748 | 0.73 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL2274341 | 0.73 | ALOX5 (0.63) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009127338-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-22 | — | — | WO | disclosed |