Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646860 | 0.85 | ALOX5 (0.54) | ALOX5ALDH1A1KMT2A | |
| SCHEMBL9645952 | 0.82 | ALOX5 (0.70) | ALOX5KDM4EALDH1A1 | |
| SCHEMBL9646895 | 0.80 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL10037024 | 0.78 | P2RX4 (0.60) | P2RX4KDM4EALDH1A1KMT2A | |
| SCHEMBL1069838 | 0.77 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL31667227 | 0.76 | MEN1 (0.61) | ALOX5P2RX4KMT2A | |
| SCHEMBL11614550 | 0.75 | PSD (0.47) | P2RX4KMT2A | |
| SCHEMBL9645961 | 0.74 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL11455491 | 0.72 | L3MBTL1 (0.48) | P2RX4KDM4EALDH1A1KMT2A | |
| SCHEMBL9453622 | 0.71 | P2RX4 (0.52) | P2RX4KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |