Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788686 | 0.72 | HSD17B10 (0.52) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL10697500 | 0.72 | HSD17B10 (0.44) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL22954113 | 0.72 | CA1 (0.40) | HSD17B10TSHRHPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL8088179 | 0.70 | CYP2D6 (0.37) | MAPK1CYP3A4LMNASLC6A2KMT2A | |
| SCHEMBL68191 | 0.69 | HSD17B10 (0.77) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL19085624 | 0.68 | F2RL3 (0.35) | HPGDMAPK1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL981107 | 0.68 | NMT1 (0.34) | — | |
| SCHEMBL18987826 | 0.65 | DRD1 (0.44) | HSD17B10CYP1A2KMT2ADRD1ALDH1A1 | |
| SCHEMBL54380 | 0.65 | HSD17B10 (1.00) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL29364629 | 0.65 | HSD17B10 (1.00) | HSD17B10TSHRHPGDMAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |