Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283982 | 0.79 | KMT2A (0.33) | SMN1; SMN2ALOX15ALDH1A1HPGDMAPT | |
| SCHEMBL2006272 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1CYP3A4MAPTKMT2A | |
| SCHEMBL10698447 | 0.72 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2ALOX15CYP1A2CYP2C9 | |
| SCHEMBL272067 | 0.72 | HSD17B10 (0.55) | HSD17B10SMN1; SMN2ALOX15CYP1A2CYP2C9 | |
| SCHEMBL5808352 | 0.70 | MEN1 (0.33) | ALOX15ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL17923137 | 0.70 | CRHR1 (0.35) | SMN1; SMN2ALOX15ALDH1A1HPGDMAPT | |
| SCHEMBL21603495 | 0.70 | LMNA (0.37) | SMN1; SMN2CYP1A2TSHRALDH1A1CYP3A4 | |
| SCHEMBL9300275 | 0.69 | ALOX15 (0.42) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL31094911 | 0.69 | MAPT (0.41) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL5638960 | 0.69 | MAPT (0.41) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |