Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450504 | 0.97 | MAOB (0.50) | MAOBCYP19A1MAOANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27774532 | 0.95 | MAOB (0.48) | MAOBCYP19A1MAOANPC1RAB9A | |
| SCHEMBL264894 | 0.76 | MAOB (0.55) | MAOBCYP19A1MAOANPC1RAB9A | |
| SCHEMBL264895 | 0.76 | MAOB (0.55) | MAOBCYP19A1MAOANPC1RAB9A | |
| SCHEMBL6058424 | 0.74 | NPC1 (0.54) | MAOBCYP19A1MAOANPC1RAB9A | |
| SCHEMBL11499268 | 0.73 | LMNA (0.59) | MAOBCYP19A1MAOALMNAIDO1 | |
| SCHEMBL16192712 | 0.73 | NFE2L2 (0.48) | NPC1RAB9ACYP2C9CYP3A4CYP2C19 | |
| SCHEMBL11499270 | 0.73 | LMNA (0.59) | MAOBCYP19A1MAOALMNAIDO1 | |
| SCHEMBL5098432 | 0.73 | — | — | |
| SCHEMBL3473864 | 0.72 | MAOB (0.50) | MAOBCYP19A1MAOANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274114-A2 | Heat curable organopolysiloxane compositions | Wacker Silicones Corporation (US) | 1988-07-13 | — | — | EP | disclosed |
| US-4710559-A | Heat curable organopolysiloxane compositions | WACKER SILICONES CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |