Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316760 | 0.82 | NPC1 (0.64) | NPC1L3MBTL1TRPM8TDP1GLA | |
| SCHEMBL10317122 | 0.82 | NPC1 (0.64) | NPC1L3MBTL1TRPM8TDP1GLA | |
| SCHEMBL11965212 | 0.81 | NPC1 (0.57) | NPC1L3MBTL1TRPM8TDP1GLA | |
| N,N-Dimethylcinnamamide SCHEMBL3743395 | 0.76 | NPC1 (0.65) | NPC1L3MBTL1TRPM8TDP1GLA | |
| N,N-Dimethylcinnamamide SCHEMBL783551 | 0.76 | NPC1 (0.65) | NPC1L3MBTL1TRPM8TDP1GLA | |
| SCHEMBL3963263 | 0.76 | TRPM8 (0.54) | NPC1L3MBTL1TRPM8TDP1GLA | |
| SCHEMBL8993860 | 0.74 | ALOX5 (0.67) | NPC1L3MBTL1TRPM8TDP1GLA | |
| SCHEMBL10457551 | 0.74 | ALOX5 (0.67) | NPC1L3MBTL1TRPM8TDP1GLA | |
| SCHEMBL11965213 | 0.73 | NPC1 (0.57) | NPC1L3MBTL1TRPM8TDP1GLA | |
| SCHEMBL7373222 | 0.73 | NPC1 (0.61) | NPC1L3MBTL1TRPM8TDP1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274546-A1 | New oxazolinone compounds useful as intermediates for the preparation of insecticidal and acaracidal cinnamide compounds | AMERICAN CYANAMID COMPANY (US) | 1988-07-20 | — | — | EP | disclosed |