Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 2/20 | 0.30 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | CPA3 | P15088 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42084 | 1.00 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL987086 | 1.00 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL10698553 | 1.00 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL9777404 | 1.00 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL11360544 | 1.00 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL10698543 | 1.00 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| Hydrogen Peroxide SCHEMBL28115963 | 1.00 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL7154950 | 0.97 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL2686163 | 0.97 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| Methane SCHEMBL9150719 | 0.97 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283156-A2 | Organosilicon sulphosuccinates | Dow Corning Limited (GB) | 1988-09-21 | — | — | EP | disclosed |